In cases of threat to life, Shabbat is suspended. Does this mean that considerations of Shabbat entirely vanish, or does it mean that you should give thought to violating Shabbat as little as possible?
Principles of handling muktse items on Shabbat, asking a non-Jew to handle them, and taking into hand a muktse item that a non-Jew hands to you.
Benefiting from the labor that non-Jews do for you on Shabbat.
Transporting the disabled through the public domain in a community that has no eiruv.